GO:0072586 molecular_function DNA topoisomerase (ATP-hydrolyzing) regulator activity
| PAG Title | GO:0072586 molecular_function DNA topoisomerase (ATP-hydrolyzing) regulator activity |
| PAG ID | TAX030074 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. |
| Species | Homo sapiens |
| nCoCo Score | 0 |
| Base PAG ID | TAX030074 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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